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KMID : 0361420020260040445
Journal of Korean Academy of Rehabilitation Medicine
2002 Volume.26 No. 4 p.445 ~ p.448
The Effect of Prolotherapy for Osteoarthritis of the Knee
±èÁ¾¹®/Jong Moon Kim
Abstract
Objective: To evaluate the effects of dextrose prolotherapy on knee osteoarthritis.

Method: The patient population consisted of 20 individuals with knee osteoarthritis. Patients have suffered from knee pain for six months or more along with Kellgren's grade 2 or more radiographical change in knee compartment. They were
injected
monthly with 15% and 25% dextrose on knee joints for 4 months. The outcome was measured by visual analogue scale (VAS) for pain, pain rating score, and WOMAC osteoarthritis index at a month after 4th injection.

Results: Seventeen of the 20 patients achieved significant diminution of pain or disability scores after dextrose prolotherapy compared with pre-treatment status. There were significant reductions in VAS score, pain rating score, and WOMAC
osteoarthritis index after dextrose injection (p£¼0.05). Three patients dropped out over follow up period due to lack of efficacy.

Conclusion: Prolotherapy injection with dextrose resulted in clinically and statistically significant improvements in knee osteoarthritis.
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